●Berberine ke Eng?
Berberine ke alkaloid ea tlhaho e ntšitsoeng metsong, kutung le makhapetla a limela tse fapaneng, joalo ka Coptis chinensis, Phellodendron amurense le Berberis vulgaris. Ke motsoako o ka sehloohong o sebetsang oa Coptis chinensis bakeng sa phello ea antibacterial.
Berberine ke kristale e mosehla e bōpehileng joaloka nale e nang le tatso e babang. Sejo se ka sehloohong se babang ho Coptis chinensis ke berberine hydrochloride. Ena ke alkaloid ea isoquinoline e ajoang litlama tse fapaneng tsa tlhaho. E fumaneha ho Coptis chinensis ka sebopeho sa hydrochloride (berberine hydrochloride). Liphuputso li fumane hore motsoako ona o ka sebelisoa ho phekola lihlahala, lefu la sebete, mafu a pelo, khatello ea mali, ho ruruha, tšoaetso ea baktheria le kokoana-hloko, letšollo, lefu la Alzheimer le ramatiki.
● Melemo ea Berberine ke Efe ea Bophelo bo Botle?
1.Antioxidant
Tlas'a maemo a tloaelehileng, 'mele oa motho o boloka ho leka-lekana pakeng tsa li-antioxidants le li-prooxidants. Khatello ea oxidative ke ts'ebetso e kotsi eo e ka bang mokena-lipakeng oa bohlokoa oa tšenyo ea sebopeho sa lisele, ka hona e baka maemo a fapaneng a mafu a kang lefu la pelo, mofets'e, mafu a methapo le lefu la tsoekere. Tlhahiso e feteletseng ea mefuta ea oksijene e sebetsang (ROS), hangata ka ho hlohlelletsa ho feteletseng ha NADPH ka li-cytokine kapa ka ketane ea lipalangoang tsa elektronike ea mitochondrial le xanthine oxidase, e ka lebisa khatellong ea oxidative. Liteko li bontšitse hore berberine metabolites le berberine li bonts'a ts'ebetso e ntle haholo -OH ea ho senya, e batlang e lekana le matla a antioxidant vithamine C. Tsamaiso ea berberine ho likhoto tsa lefu la tsoekere e ka shebella ho eketseha ha mosebetsi oa SOD (superoxide dismutase) le ho fokotseha ha MDA (a) letšoao la lipid peroxidation) maemo [1]. Liphetho tse ling li bonts'a hore ts'ebetso ea ho hloekisoa ha berberine e amana haufi-ufi le ts'ebetso ea eona ea ferrous ion chelating, 'me sehlopha sa C-9 hydroxyl sa berberine ke karolo ea bohlokoa.
2. Anti-tumor
Ho bile le litlaleho tse ngata mabapi le phello e khahlanong le mofetše oaberberine. Liphuputso tse fapa-fapaneng lilemong tsa morao tjena li bontšitse hore berberine e bohlokoa haholo kalafong ea adjuvant ea mafu a tebileng a mofets'e joalo ka mofets'e oa mahe a bomme, mofets'e oa endometrial, mofets'e oa popelo, mofets'e, mofets'e oa matšoafo, mofets'e oa colorectal, mofets'e oa liphio, mofets'e oa senya le mofets'e oa senya. [2]. Berberine e ka thibela ho ata ha lisele tsa hlahala ka ho sebelisana le lipheo le mekhoa e fapaneng. E ka fetola polelo ea li-oncogenes le liphatsa tsa lefutso tse amanang le kankere ho finyella morero oa ho laola mosebetsi oa li-enzyme tse amanang le tsona ho thibela ho ata.
3.Ho Fokotsa Lipids tsa Mali Le ho Sireletsa Sisteme ea pelo
Berberine e bapala karolo ea bohlokoa kalafong ea mafu a pelo le methapo mme e na le lits'ebetso tse fapaneng. Berberine e finyella sepheo sa anti-arrhythmia ka ho fokotsa liketsahalo tsa ho otla pele ho nako ea ventricular le ho thibela ho etsahala ha ventricular tachycardia. Taba ea bobeli, dyslipidemia ke sesosa se seholo sa kotsi bakeng sa lefu la pelo, le khetholloang ke maemo a phahameng a cholesterol eohle, triglycerides, le low-density lipoprotein cholesterol (LDL), le maemo a fokotsehileng a high-density lipoprotein (HDL), le berberine e ka boloka matla a matla. botsitso ba matšoao ana. Hyperlipidemia ea nako e telele ke sesosa sa bohlokoa sa ho theha letlapa la atherosclerotic. Ho tlalehoa hore berberine e ama li-receptor tsa LDL ho li-hepatocyte ho fokotsa maemo a k'holeseterole ea serum ea batho ho hepatocyte. Eseng hoo feela,berberinee na le phello e ntle ea inotropic mme e sebelisitsoe ho phekola ho hloleha ha pelo ea congestive.
4.E theola Tsoekere ea Mali 'me e Laola Endocrine
Diabetes mellitus (DM) ke lefu la metabolism le khetholloang ke maemo a phahameng a tsoekere maling (hyperglycemia) a bakoang ke ho sitoa ha lisele tsa pancreatic B ho hlahisa insulin e lekaneng, kapa ho lahleheloa ke karabelo e sebetsang ea lithane tsa insulin. Phello ea hypoglycemic ea berberine e fumanoe ka phoso lilemong tsa bo-1980 kalafong ea bakuli ba nang le lefu la tsoekere ba nang le letšollo.
Liphuputso tse ngata li bontšitse seoberberinee theola tsoekere maling ka mekhoa e latelang:
● E thibela oxidation ea tsoekere ea mitochondrial le ho susumetsa glycolysis, ka mor'a moo e eketsa metabolism ea tsoekere;
● E fokotsa maemo a ATP ka ho thibela mosebetsi oa mitochondrial sebeteng;
● E thibela ts'ebetso ea DPP 4 (serine protease e fumanehang hohle), kahoo e qhekella li-peptide tse itseng tse sebetsang ho eketsa maemo a insulin ka pel'a hyperglycemia.
● Berberine e na le phello e molemo ho ntlafatseng ho hanyetsa insulin le ho sebelisoa ha tsoekere ka har'a lisele ka ho fokotsa lipids (haholo-holo triglycerides) le boemo ba plasma ea mafura a mahala.
Kakaretso
Matsatsing ana,berberinee ka etsoa ka maiketsetso le ho fetoloa ka mekhoa ea boenjiniere ba kristale. E na le theko e tlase le theknoloji e tsoetseng pele. Ka nts'etsopele ea lipatlisiso tsa bongaka le ho teba ha lipatlisiso tsa lik'hemik'hale, berberine e tla bontša liphello tse ngata tsa meriana. Ka lehlakoreng le leng, berberine ha e fumane feela liphello tse tsotehang lipatlisisong tsa setso tsa meriana ea antibacterial, antiviral, anti-inflammatory, anti-tumor, anti-diabetic, le phekolo ea mafu a pelo le cerebrovascular, empa hape le moralo oa eona oa boenjiniere ba kristale le tlhahlobo ea morphological. li fumane tlhokomelo e kholo. Ka lebaka la ts'ebetso ea eona ea bohlokoa le chefo e tlase le litlamorao, e na le monyetla o moholo ts'ebelisong ea bongaka 'me e na le menyetla e mengata. Ka nts'etsopele ea biology ea lisele, mokhoa oa pharmacological oa berberine o tla hlakisoa ho tloha boemong ba lisele tsa cellular esita le maemo a limolek'hule le sepheo, ho fana ka motheo oa khopolo-taba bakeng sa ts'ebeliso ea eona ea bongaka.
● NEWGREEN SupplyBerberine/Liposomal Berberine Powder/Capsules/Tablets
Nako ea poso: Oct-28-2024
