Ke Eng?Ginsenosides?
Ginsenosides ke metsoako ea bohlokoa e sebetsang ea ginseng. Ke tsa metsoako ea triterpenoid glycoside 'me e ka aroloa ka protopanaxadiol saponins (PPD-mofuta oa saponins), protopanaxatriol saponins (PPT-mofuta oa saponins) le mofuta oa oleanane. Li-ginsenoside tse fetang 40 li qheletsoe ka thoko ho metso ea ginseng.
Ginsenosides e na le litlamorao tse ngata tsa kalafo joalo ka antioxidant, anti-inflammatory, vasodilation, anti-allergic, le anti-diabetic. Li-ginsenosides tse ling li bonts'a thepa ea tsona e khahlanong le mofets'e ka ho fokotsa ts'enyo ea DNA, ho fokotsa ts'oaetso ea moamoheli ho liphetoho, ho eketsa tlhokomeliso ea 'mele ea ho itšireletsa mafung le apoptosis ea lisele. Ho feta moo, ginsenosides e ka ntlafatsa katleho ea meriana ea setso ea chemotherapy le ho thibela tšenyo ea lisele tse tloaelehileng.
Litaba tsa Kakaretso ea Ginsenosides Likarolong tse fapaneng tsa Ginseng
| Karolo | Kakaretso ea Ginsenosides Content |
| Metso e ka morao | 60.5% |
| Li-buds | 15% |
| Makhasi a Ginseng | 7.6%-12.6% |
| Ginseng metso ea fibrous | 8.5%-11.5% |
| Letlalo la Ginseng | 8.0%-8.8% |
| Motsoako oa ginseng | 2%-7% |
| Ginseng metso e nyane | 3% |
| Peo | 0.7% |
Mefuta le Lits'ebetso tsa Lik'hemik'hale TsaGinsenosides
Li-ginsenosides kaofela li na le libopeho tsa motheo tse tšoanang, kaofela li na le nucleus ea sterane steroid e nang le liathomo tsa carbon tse 30 tse hlophisitsoeng ka mehele e mene. Li arotsoe ka lihlopha tse peli ho latela meaho e fapaneng ea glycoside: mofuta oa dammarane le mofuta oa oleanane.
Mofuta oa Dammarane o kenyelletsa mekhahlelo e 'meli:
Ginsenoside mofuta-A, aglycone ke 20 (S) -protopanaxadiol. E na le li-ginsenosides tse ngata, tse kang ginsenoside Rg3, Rb1, Rb2, Rb3, Rc, Rd, Rh2 le glycoside PD;
Ginsenoside mofuta-B, aglycone ke 20 (S) -protopanaxadiol. E na le ginsenoside Re, Rg1, Rg2, Rh1 le glycoside PT.
Mofuta oa Oleanane: oleanolic acid mofuta-C, aglycone ke oleanolic acid.
Kakaretso ea saponins ha e na hemolytic, mofuta oa A o khahlanong le hemolytic, ha mofuta oa B le mofuta oa C ke oa hemolytic.
| Mefuta ea Ginsenoside | Katleho |
| Rh2 | E na le phello ea ho thibela metastasis ea lisele tsa mofetše ho litho tse ling, ho matlafatsa sesole sa 'mele, le ho khutlisa kapele ho phela hantle 'meleng. E na le phello e kholo ea anti-metastasis liseleng tsa mofetše, 'me e ka nkuoa ka opereishene ho ntlafatsa pholiso ea maqeba le ho hlaphoheloa ha' mele kamora ho buuoa. Bioavailability e felletseng ke (16.1±11.3)%. |
| Rg | E na le phello ea ho susumetsa tsamaiso ea methapo e bohareng, ho hanela mokhathala, ho ntlafatsa mohopolo le bokhoni ba ho ithuta, le ho khothalletsa DNA le RNA synthesis. E na le phello ea ho susumetsa tsamaiso ea methapo e bohareng, ho hanela mokhathala, ho ntlafatsa mohopolo le bokhoni ba ho ithuta, le ho khothalletsa DNA le RNA synthesis. |
| Rg1 | E ka imolla mokhathala kapele, ea ntlafatsa ho ithuta le ho hopola, le ho liehisa botsofali. E na le phello ea ho susumetsa tsamaiso ea methapo e bohareng le ho thibela platelet aggregation. |
| Rg2 | E na le phello ea anti-shock, ka potlako e ntlafatsa myocardial ischemia le hypoxia, 'me e phekola le ho thibela lefu la pelo. |
| Rg3 | E ka nka khato karolong ea G2 ea potoloho ea ho ikatisa ea lisele, ea thibela motsoako oa liprotheine le ATP karolong ea pele ho mitotic ea lisele tsa mofetše, ea liehisa ho ata le ho hola ha lisele tsa mofetše, 'me e na le litlamorao tsa ho thibela ho kenella ha lisele tsa mofets'e, ho hanela tumor cell metastasis, ho khothaletsa tumor cell apoptosis, le ho thibela kholo ea lisele tsa tumor. |
| Rg5 | Thibela ho kenella ha lisele tsa mofets'e, anti-tumor cell metastasis, ho khothaletsa tumor cell apoptosis, ho thibela kholo ea lisele tsa tumor. |
| Rb1 | American ginseng (American ginseng) e na le litaba tse phahameng ka ho fetisisa 'me e na le bokhoni ba ho ama li-testicles tsa liphoofolo le tsoelo-pele ea embryonic ea litoeba. E na le mosebetsi oa ho ntlafatsa tsamaiso ea choline, ho eketsa motsoako le ho lokolloa ha acetylcholine le ho ntlafatsa mohopolo. |
| Rb2 | DNA le RNA tlhahiso ea motsoako, taolo ea setsi sa boko e na le liphello tsa ho thibela tsamaiso ea methapo e bohareng, ho fokotsa k'halsiamo ea intracellular, anti-oxidation, ho senya li-radicals tsa mahala 'meleng le ho ntlafatsa kotsi ea myocardial ischemia-reperfusion. |
| Rc | Ginsenoside-Rc ke molek'hule ea steroid ka ginseng. E na le mosebetsi oa ho thibela lisele tsa mofetše. E ka eketsa mosebetsi oa peō ea botona. |
| Rb3 | E ka ntlafatsa ts'ebetso ea myocardial le ho sireletsa sesole sa 'mele. E ka sebelisoa ho phekola ho hloleha ha contractile ea myocardial ho bakoang ke mabaka a fapaneng. |
| Rh | E na le litlamorao tsa ho thibela tsamaiso ea methapo e bohareng, hypnotic, analgesic, khutso, antipyretic, le ho khothaletsa serum protheine synthesis. |
| Rh1 | E na le liphello tsa ho khothalletsa ho ata ha lisele tsa sebete le motsoako oa DNA, 'me e ka sebelisoa ho phekola le ho thibela lefu la sebete le ho thatafala ha sebete. |
| R0 | E na le li-anti-inflammatory, detoxifying, le anti-thrombotic effects, e thibela ho kopana ha liplatelete tsa acidic, 'me e na le liphello tse khahlanong le lefu la sebete' me e kenya tšebetsong macrophages. |
| Rh3 | Liphello tsa ginsenoside Rh3 ho ata le apoptosis ea lisele tsa mofetše oa motho SW480. |
Lisebelisoa tsa anti-tumor
| Lisebelisoa | Katleho |
| Rh2 | Ginsenoside Rh2 monomer e na le phello e thibelang kholo ea lisele tsa mofetše, e ka etsa hore tumor cell apoptosis, e fetole phapang e sa tloaelehang ea lisele tsa tumor, 'me e hanele metastasis ea tumor. Ha e sebelisoa hammoho le lithethefatsi tsa chemotherapy, e ka ntlafatsa ts'ebetso le ho fokotsa chefo. Ntle le phello e khahlanong le hlahala, ginsenosides e na le litlamorao tsa ho ntlafatsa ts'ireletso ea 'mele, antibacterial, ho ntlafatsa phallo ea mali ea pelo le methapo ea mali, ho laola tsamaiso ea methapo e bohareng, anti-mokhathala le ho lieha ho tsofala. |
| Rh1 | E ka thibela ho khomarela le ho kenella ha lisele tsa hlahala, ho thibela ho thehoa ha methapo e mecha ea mali bakeng sa lisele tsa mofetše, kahoo e thibela ho hōla ha hlahala, ho ata le metastasis, 'me e na le ts'ebetso ea bohlokoa e khahlanong le mofetše. E ka ntlafatsa haholo phokotso ea lisele tse tšoeu tsa mali tse bakoang ke radiotherapy, chemotherapy le opereishene, 'me ea etsa hore rheology ea mali e be e tloaelehileng. Sejo sena se na le phello e matla ea thibelo le e khahlanong le mofetše, e ka ntlafatsa ts'ebetso ea motho le ts'ebetso ea 'mele ea ho itšireletsa mafung,' me e na le liphello tse kholo hammoho le ho buuoa le radiotherapy le chemotherapy. |
| Rg5 | Rg5 e ka baka apoptosis ea lisele tse fapaneng tsa tumor. Rg5 e ntšitsoeng ho ginseng e ntšo e ntle e netefalitsoe liseleng tsa matsoele a motho. Rg5 e ka boela ea baka tšenyo ea apoptosis le DNA liseleng tse fapaneng tsa mofetše oa popelo. Aseries of in vitro liteko li netefalitse hore ginsenoside Rg5 e na le phello e thibelang lisele tsa mofetše oa esophageal. |
| Rh3 | Ginsenoside Rh3 e ka thibela ho ata ha lisele tsa mofetše oa mala oa motho SW480 le ho susumetsa apoptosis, 'me phello e itšetlehile ka tekanyo le nako. |
| APPD | 20 (S) - Protopanaxadiol (aPPD) ke motsoako o sebetsang o nang le katleho ea lithethefatsi e hlahisoang ke ginsenosides ka mor'a metabolism ea desugar le ts'ebetso ea limela tsa mala, 'me e na le liphello tse ngata tse khahlanong le hlahala. Lilemong tsa morao tjena, sehlopha sa lipatlisiso sa William Jia sa Univesithi ea British Columbia se entse letoto la liphuputso mabapi le ts'ebetso ea anti-tumor ea PPD in vivo le in vitro, mme e fumane hore e na le litlamorao tse peli tsa pharmacological. Ka lehlakoreng le leng, e ka bolaea lisele tsa hlahala ka kotloloho le ho khothaletsa apoptosis ea tsona; ka lehlakoreng le leng, e ka sireletsa li-neurone linthong tsa cytotoxic. |
Molemo oaGinsenosides?
Melemo ea ginsenosides, metsoako e sebetsang e fumanoang ho ginseng, e pharaletseng 'me e bile taba ea lipatlisiso tse pharaletseng. Melemo e meng e ka bang teng ea ginsenosides e kenyelletsa:
1. Mosebetsi oa Kelello: Ginsenosides e 'nile ea ithutoa bakeng sa bokhoni ba bona ba ho tšehetsa ts'ebetso ea kelello, ho kenyelletsa mohopolo, ho tsepamisa maikutlo le ho hlaka kelellong.
2. Matla le Matla: Ho lumeloa hore Ginsenosides e na le thepa ea adaptogenic, e thusang ho tšehetsa maemo a matla, ho fokotsa mokhathala, le ho khothalletsa matla ka kakaretso.
3. Tšehetso ea Tšireletso ea 'mele: Liphuputso tse ling li fana ka maikutlo a hore ginsenosides e na le liphello tsa ho itšireletsa mafung, tse ka' nang tsa tšehetsa karabelo ea 'mele ea ho itšireletsa mafung.
4. Stress Management: Ginsenosides e nkoa e le adaptogens, e bolelang hore e thusa 'mele ho ikamahanya le khatello ea kelello le ho khothalletsa boikutlo ba boiketlo.
5. Bophelo bo Botle ba Methapo: Liphuputso tse ling li hlahlobile bokhoni ba ginsenosides ho tšehetsa bophelo bo botle ba pelo, ho kenyelletsa le liphello tsa bona khatellong ea mali le ho potoloha ha mali.
Ho bohlokoa ho hlokomela hore melemo e ikhethang ea ginsenosides e fapana ho latela mofuta oa ginseng le sebopeho sa li-ginsenoside tse teng. Joalo ka tlatsetso efe kapa efe kapa sehlahisoa sa tlhaho, ho bohlokoa ho buisana le setsebi sa tlhokomelo ea bophelo bakeng sa likeletso tsa motho ka mong mabapi le ts'ebeliso ea ginsenosides bakeng sa mathata a itseng a bophelo bo botle.
Lisebelisoa tsa Ginsenosides ke Eng?
Ginsenosides e na le mefuta e mengata ea ts'ebeliso e ka bang teng ka lebaka la thepa ea bona e fapaneng ea pharmacological. Tse ling tsa ts'ebeliso ea ginsenosides li kenyelletsa:
1. Meriana ea Tloaelo: Ginsenosides e 'nile ea sebelisoa ka lilemo tse makholo meriana ea setso, haholo-holo Asia Bochabela, bakeng sa thepa ea bona ea adaptogenic le ea bophelo bo botle.
2. Li-Supplement: Hangata Ginsenosides e sebelisoa e le metsoako e sebetsang ho li-supplement tsa lijo le litokisetso tsa litlama tse reretsoeng ho tšehetsa ts'ebetso ea kelello, matla a matla, le bophelo bo botle ka kakaretso.
3. Meriana ea Meriana: Lipatlisiso mabapi le mekhoa ea phekolo ea ginsenosides e lebisitse ho sebelisoa ha tsona lihlahisoa tsa meriana, haholo-holo ho nts'etsopele ea meriana bakeng sa maemo a kang ho fokotseha ha kelello, mokhathala, le mathata a amanang le khatello ea kelello.
4. Litlolo: Li-ginsenosides li boetse li sebelisoa indastering ea litlolo bakeng sa melemo ea tsona ea letlalo, ho kenyelletsa le thepa e thibelang botsofali le antioxidant.
5. Lijo le Lijo tse Sebetsang: Ginsenosides e kenyelelitsoe lijong tse sa tšoaneng tse sebetsang le lino tse tahang, tse kang lino tse matla le li-tonic tsa bophelo bo botle, ho fana ka melemo ea bophelo bo botle.
Ke Efe Setlamorao EaGinsenosides?
Ginsenosides ka kakaretso e nkuoa e bolokehile ha e sebelisoa ka litekanyetso tse nepahetseng, empa joalo ka motsoako ofe kapa ofe oa bioactive, e ka ba le litlamorao tse ka bang teng, haholo ha e jeoa ka bongata. Litla-morao tse ling tse ka bang teng tsa ginsenosides li ka kenyelletsa:
1. Ho hlobaela: Litekanyetso tse phahameng tsa ginsenosides li ka baka ho tsosoa ho feteletseng, tse lebisang ho thatafalloa ke ho robala kapa ho robala.
2. Mathata a Tšhilo ea Lijo: Batho ba bang ba ka ’na ba ba le bothata ba ho sila lijo, joalo ka ho nyekeloa ke pelo, letšollo, kapa ho ferekana ke mala, ha ba noa tekanyo e phahameng ea ginsenosides.
3. Khatello ea mali: Maemong a sa tloaelehang, tšebeliso e feteletseng ea ginsenosides e ka lebisa khatellong e phahameng ea mali.
4. Lintho Tse Amanang le Lintho Tse Ngata: Le hoja li sa tloaeleha, batho ba bang ba ka ’na ba hanana le ginsenosides, e leng se etsang hore ba be le matšoao a kang lekhopho, ho hlohlona kapa ho hema ka thata.
5. Liphello tsa Hormonal: Ginsenosides e ka 'na ea e-ba le liphello tse bonolo tsa li-hormone,' me maemong a mang, li ka sebelisana le meriana kapa maemo a amanang le hormone.
Ke habohlokoa ho hlokomela hore litla-morao tsa ginsenosides li ka fapana ho itšetlehile ka motho ka mong, mofuta o itseng oa ginseng, le litekanyetso. Joalo ka tlatsetso efe kapa efe kapa sehlahisoa sa tlhaho, ho bohlokoa ho buisana le setsebi sa tlhokomelo ea bophelo pele u sebelisa ginsenosides, haholo-holo ho ba nang le maemo a bophelo bo botle kapa ba noang meriana.
Lipotso Tse Amanang le Ena U ka li Thahasella:
Ke mang ea sa lokelang ho noa ginseng?
Batho ba bang ba lokela ho ba hlokolosi kapa ba qobe ho noa ginseng, ho kenyelletsa:
1. Basali ba Bakhachane kapa ba Anyesang: Tšireletseho ea ginseng nakong ea bokhachane le ho anyesa ha e e-s'o ithutoe ka mokhoa o pharaletseng, kahoo hangata ho buelloa ho qoba tšebeliso ea eona linakong tsena.
2. Batho ba nang le Mathata a Autoimmune: Ginseng e ka 'na ea susumetsa sesole sa' mele, se ka 'nang sa mpefatsa maemo a autoimmune. Ho eletsoa hore batho ba nang le mathata a autoimmune ba buisane le setsebi sa bophelo bo botle pele ba sebelisa ginseng.
3. Batho ba nang le Mathata a ho Tlisa Mali: Ginseng e ka 'na ea e-ba le liphello tse fokolang tsa anticoagulant, kahoo batho ba nang le bothata ba ho tsoa mali kapa ba noang meriana e fokotsang mali ba lokela ho sebelisa ginseng ka hloko le tlas'a tataiso ea mofani oa tlhokomelo ea bophelo.
4. Batho ba nang le Maemo a Thibelang Lihomone: Ka lebaka la litlamorao tse ka bang teng tsa lihomone tsa ginseng, batho ba nang le maemo a amehang ka lihormone joalo ka mofetše oa matsoele, uterine fibroids, kapa endometriosis ba lokela ho ikopanya le setsebi sa tlhokomelo ea bophelo pele ba sebelisa ginseng.
5. Ba nang le Mathata a ho Hlobaela Kapa a ho Tšoenyeha: Ginseng e ka ’na ea e-ba le liphello tse hlasimollang, kahoo batho ba nang le bothata ba ho hlobaela kapa ba tšoenyehileng ba lokela ho ba hlokolosi ha ba sebelisa ginseng, haholo-holo ha ba e noa haholo.
Na ginsenosides ke li-steroid?
Ginsenosides ha se li-steroids. Ke sehlopha sa metsoako ea tlhaho e fumanoang semeleng sa ginseng. Le hoja li-ginsenosides li ka ba le melemo e sa tšoaneng ea bophelo bo botle, li fapane ka mokhoa o hlophisitsoeng le o sebetsang ho li-steroids. Li-steroids ke sehlopha sa lihomone le lipids tse bapalang karolo ea bohlokoa ho metabolism ea 'mele, tšebetso ea' mele ea ho itšireletsa mafung le lits'ebetsong tse ling tsa 'mele. Ka lehlakoreng le leng, li-ginsenosides ke saponins, mofuta oa motsoako oa glycoside, 'me li tsebahala ka thepa ea tsona ea adaptogenic le ho ntlafatsa bophelo bo botle.
Ke ginseng efe e nang le eona e phahameng ka ho fetisisaginsenosides?
Mofuta oa ginseng o nang le li-ginsenoside tse phahameng ka ho fetisisa ke Panax ginseng, e tsejoang hape e le Asian kapa Korean ginseng. Mofuta ona oa ginseng o tsejoa ka bongata ba eona bo bongata ba ginsenosides, e leng metsoako ea bioactive e ikarabellang molemong oa bophelo bo botle ba semela. Panax ginseng e nkoa e le ea bohlokoa haholo meriana ea setso 'me e atisa ho sebelisoa bakeng sa thepa ea eona ea adaptogenic le e matlafatsang. Ha u batla lihlahisoa tsa ginseng tse nang le litaba tse phahameng tsa ginsenoside, Panax ginseng ke khetho e tsebahalang.
Na ho loketse ho noa ginseng letsatsi le leng le le leng?
Ka kakaretso ho nkoa e sireletsehile hore batho ba bangata ba noe ginseng letsatsi le leng le le leng ka nako e khutšoanyane. Leha ho le joalo, tšebeliso ea nako e telele ea letsatsi le letsatsi ea ginseng e ka lebisa litla-morao tse ka bang teng kapa ho sebelisana le meriana. Ka hona, ho bohlokoa ho sebelisa ginseng tlas'a tataiso ea setsebi sa tlhokomelo ea bophelo, haholo-holo haeba u rerile ho e noa letsatsi le leng le le leng ka nako e telele. Ho buisana le mofani oa tlhokomelo ea bophelo ho ka thusa ho netefatsa hore ginseng e loketse litlhoko tsa hau tsa bophelo bo botle le hore ha e sebelisane le meriana leha e le efe kapa maemo a neng a le teng pele.
Na ginseng e eketsa testosterone?
Ginseng e khothalelitsoe ho ba le litlamorao tse ka bang teng maemong a testosterone, leha bopaki bo sa phethehe. Liphuputso tse ling li bontšitse hore ginseng e ka ba le phello e itekanetseng maemong a testosterone, mohlomong ka ho tšehetsa mekhoa e amehang tlhahisong ea testosterone. Leha ho le joalo, ho hlokahala lipatlisiso tse eketsehileng ho utloisisa ka botlalo boholo ba tšusumetso ea ginseng ho testosterone.
Ginseng e etsa'ng ho li-hormone tsa basali?
Ginseng e ka 'na ea e-ba le liphello tse ka' nang tsa e-ba teng ho li-hormone tsa basali, le hoja lipatlisiso sebakeng sena li sa phethe ka botlalo. Boithuto bo bong bo bontšitse hore ginseng e kanna ea ba le thepa ea adaptogenic e ka thusang ho ts'ehetsa botsitso ba lihormone ho basali, haholo nakong ea khatello ea maikutlo kapa ho feto-fetoha ha li-hormone. Ho phaella moo, ginseng e 'nile ea hlahlojoa bakeng sa melemo ea eona e ka bang teng ho sebetsana le matšoao a amanang le ho khaotsa ho ilela khoeli, a kang ho chesa le ho fetoha ha maikutlo.
Nako ea poso: Sep-12-2024
