Ke Eng?Glabridin?
Glabridin ke flavonoid e ntšitsoeng metsong ea licorice (Glycyrrhiza glabra) 'me e na le mesebetsi e fapaneng ea likokoana-hloko le melemo ea bophelo bo botle. glabridin e tsejoa ka matla a eona a bosoeu, antioxidant le anti-inflammatory properties 'me e sebelisoa haholo ho hlokomela letlalo le litlolo.
Glycyrrhiza glabra L. ke setlama se sa feleng se melang karolong e ka boroa ea Europe, Asia le sebakeng sa Mediterranean. E jalwa haholo Russia, Spain, Iran le India. Semela sa G. glabra se ka ba bolelele ba limithara tse 1-1.5, se na le makhasi a manyenyane a botala bo lefifi, lipalesa tse mosehla, tse putsoa le tse violet, le rhizome e monate.
Glabridin ke e 'ngoe ea li-flavonoids tse ka sehloohong ho Glycyrrhiza glabra. E bonts'a phello e matla ea anti-free radical oxidation ho cytochrome P450 / NADPH oxidation system, mme e ka thibela haholo li-radicals tsa mahala tse hlahisoang nakong ea ts'ebetso ea metabolism 'meleng ho thibela li-biomacromolecules tsa oxidation (low-density lipoprotein LDL, DNA) le mabota a lisele ho tloha ho senyeha ka lebaka la oxidation ea mahala. Sena se ka thibela le ho phekola liphetoho tse itseng tsa pathological tse amanang le oxidation ea mahala, joalo ka atherosclerosis le botsofali ba lisele. Ho phaella moo, glabridin e na le phello e itseng ea ho fokotsa lipids ea mali le khatello ea mali. Lipatlisiso tsa Italy li boetse li tiisitse hore Glabridin e na le phello e thibelang takatso ea lijo, e ka fokotsang mafura ntle le ho fokotsa boima ba 'mele. Ka mor'a liteko tse pheta-phetoang, liphello tse kholo ke tse latelang: 1. Whitening, inhibiting melanin; 2. Phello e khahlanong le ho ruruha; 3. Phello ea Antioxidant; 4. Antibacterial.
Thepa ea 'Mele le ea Lik'hemik'hale eaGlabridin
1. Sebopeho sa Lik'hemik'hale
Lebitso la lik'hemik'hale: Glabridin
Mokhoa oa lik'hemik'hale: C20H20O4
Boima ba 'mele: 324.37 g / mol
Litšobotsi tsa Sebopeho: Glabridin ke motsoako oa flavonoid o nang le sebopeho se tloaelehileng sa mokokotlo oa flavonoid. E na le mehele e 'meli e nkhang hamonate (A le B) e kopantsoeng ke borokho ba carbon tse tharo bo etsang lesale le koetsoeng la pyran .
2. Thepa ea 'Mele
Ponahalo: Glabridin hangata e hlaha e le phofo e tšoeu kapa e mosehla oa kristale.
Sollubility:
Metsi: Ha a qhibilihe hampe ka metsing.
Organic Solvents: E qhibiliha ka har'a metsoako ea tlhaho e kang ethanol, methanol le propylene glycol.
Sebaka se qhibilihang: Hoo e ka bang 156-158 ° C (313-316 ° F).
Monko: Glabridin ka kakaretso ha e na monko o ikhethang.
3. Lintho tsa Lik'hemik'hale
Botsitso: Glabridin e batla e tsitsitse tlas'a maemo a tloaelehileng empa e ka senyeha ha e pepesehetse khanya, mocheso kapa maemo a asiti. Ho khothalletsoa ho e boloka sebakeng se phodileng, se omeletseng, hole le letsatsi le tobileng.
pH Sensitivity: Glabridin e na le kutloelo-bohloko ho liphetoho tsa pH 'me e ka senyeha libakeng tse nang le asiti e ngata kapa tsa motheo.
Reactivity: Joaloka flavonoid, glabridin e ka ba le liphetoho tse tloaelehileng tsa lik'hemik'hale tse amanang le metsoako ea phenolic, e kang oxidation le conjugation.
Melemo ea Ke EfeGlabridin?
1. Letlalo le Lesoeu le ho Khanya
- Thibelo ea Tyrosinase: Glabridin e tsebahala haholo ka thepa ea eona e soeufatsang letlalo. E thibela tšebetso ea tyrosinase, enzyme ea bohlokoa bakeng sa tlhahiso ea melanin, ka hona e fokotsa sebopeho sa matheba a lefifi le hyperpigmentation.
- Esita le Letlalo la Letlalo: Ka ho fokotsa motsoako oa melanin, glabridin e thusa ho etsa hore letlalo le be le letlalo le khanyang haholoanyane.
2. Lintho tsa Antioxidant
- Free Radical Scavenging: Glabridin e na le thepa e matla ea antioxidant, e thusang ho fokotsa li-radicals tsa mahala. Sena se fokotsa khatello ea oxidative mme se thibela tšenyo ea lisele.
- Anti-Botsofali: Ts'ebetso ea antioxidant ea glabridin e thusa ho fokotsa matšoao a botsofali, joalo ka mela e metle, wrinkles le matheba a lilemo, ka ho sireletsa letlalo ho senyeha ha oxidative.
3. Liphello tse khahlanong le ho ruruha
- Phokotso ea Ho ruruha: Glabridin e bonts'a thepa e khahlanong le ho ruruha, e thusang ho fokotsa ho ruruha ha letlalo, bofubelu le ho ruruha.
- Phello e thobang: E ka thoba letlalo le halefileng 'me e molemo bakeng sa maemo a kang makhopho, eczema le rosacea.
4. Mosebetsi oa Antimicrobial
- Thibelo ea Likokoana-hloko: Glabridin e bontšitse thepa ea antimicrobial khahlanong le libaktheria tse sa tšoaneng le li-fungus. Sena se etsa hore e be molemo ho thibela le ho phekola mafu a letlalo.
- Kalafo ea Lihloba: Lintho tsa eona tse thibelang likokoana-hloko le tse thibelang ho ruruha li etsa hore glabridin e atlehe ho phekola maqoqomete ka ho fokotsa kholo ea baktheria le ho ruruha.
5. Tšireletso ea UV
- Photoprotection: Glabridin e ka fana ka boemo bo itseng ba tšireletso khahlanong le mahlaseli a UV. E thusa ho fokotsa tšenyo ea letlalo e bakoang ke UV, joalo ka ho chesoa ke letsatsi le ho etsa photoaging.
- Synergistic Effect: Ha e sebelisoa hammoho le lisebelisoa tse ling tse sireletsang letsatsi, glabridin e ka ntlafatsa phello ea photoprotective ka kakaretso.
6. Pholiso ea Leqeba
- E khothalletsa Pholiso: Glabridin e ka khothalletsa pholiso ea maqeba ka ho fokotsa ho ruruha le khatello ea oxidative, le ka ho susumetsa ho tsosolosoa ha lisele tsa letlalo.
- Phokotso ea Leqeba: E ka boela ea thusa ho fokotsa ponahalo ea maqeba ka ho khothaletsa nchafatso ea letlalo e phetseng hantle.
7. Tlhokomelo ea Moriri
- Bophelo bo Botle ba Letlalo: Lintho tsa Glabridin tse khahlanong le ho ruruha le likokoana-hloko li ka thusa bophelo bo botle ba letlalo la hlooho, ho fokotsa dandruff le ho hlohlona ha letlalo.
- Khōlo ea Moriri: Ka ho ntlafatsa bophelo bo botle ba letlalo la hlooho, glabridin e ka boela ea khothalletsa khōlo e ntle ea moriri.
Ke Likopo life tsaGlabridin?
Litlolo le Tlhokomelo ea Letlalo
1.Skin Whitening Products
- Li-Whitening Creams le Serums: Glabridin ke motsoako oa bohlokoa ho lihlahisoa tse ngata tsa letlalo le khanyang ka lebaka la bokhoni ba eona ba ho thibela mosebetsi oa tyrosinase le ho fokotsa tlhahiso ea melanin.
- Spot Treatments: E sebelisoa mefuteng e reretsoeng ho fokotsa matheba a lefifi, hyperpigmentation le 'mala o sa tšoaneng oa letlalo.
2.Anti-Aging Products
- Anti-Aging Creams and Lotions: Thepa ea antioxidant ea glabridin e thusa ho fokotsa matšoao a botsofali, joalo ka mela e metle, wrinkles le matheba a lilemo.
- Litlolo tsa Mahlo: Hangata li kenyeletsoa ka har'a litlolo tsa mahlo ho fokotsa selikalikoe se lefifi le boikhohomoso.
3.Lihlahisoa tse khahlanong le ho ruruha le tse thobang
- Li-gel le Litlolo tse thobang: Lintho tse khahlanong le ho ruruha tsa Glabridin li etsa hore e tšoanelehe bakeng sa lihlahisoa tse etselitsoeng ho thoba letlalo le halefileng kapa le chesang.
- Litlhare tsa Mahloba: E sebelisoa lihlahisoa tsa kalafo ea makhopho ho fokotsa ho ruruha le kholo ea baktheria.
Lihlahisoa tsa 4.Sun Protection
- Li-sunscreens: Glabridin e ka kenyelletsoa litlolo tsa letsatsi ho fana ka tšireletso e eketsehileng khahlanong le tšenyo ea letlalo e bakoang ke UV.
- Tlhokomelo ea ka mor'a letsatsi: E sebelisoa lihlahisoa tsa ka mor'a letsatsi ho thoba le ho lokisa letlalo le chesitsoeng ke letsatsi.
Meriana ea meriana
1. Meriana ea Lihlooho
- Li-Anti-Inflammatory Creams: Li sebelisoa meriana ea lihlooho ho phekola maemo a ho ruruha a letlalo a kang eczema, psoriasis le dermatitis.
- Mafura a Fokotsang Maqeba: A kenyelelitsoe mekhoeng e reretsoeng ho khothalletsa pholiso ea maqeba le ho fokotsa ho hlaha ha lebali.
2. Litlatsetso tsa Molomo
- Antioxidant Supplements: Glabridin's antioxidant properties e etsa hore e be motsoako oa bohlokoa ho li-supplement tsa molomo tse reretsoeng ho fokotsa khatello ea oxidative le ho khothalletsa bophelo bo botle ka kakaretso.
- Li-Immune Boosters: E sebelisoa ho li-supplement tse etselitsoeng ho ntlafatsa ts'ebetso ea 'mele ea ho itšireletsa mafung ka lebaka la thepa ea eona e khahlanong le ho ruruha le ea antimicrobial.
Tlhokomelo ea Moriri
1.Kalafo ea Letlalo
- Anti-Dandruff Shampoos: Antimicrobial le thepa ea anti-inflammatory ea Glabridin e etsa hore e atlehe ho phekola dandruff le ho hlohlona ha hlooho.
- Li-Serum tsa Letlalo: Li sebelisoa ka har'a li-serum tsa letlalo ho khothaletsa tikoloho e phetseng hantle ea letlalo la hlooho le ho khothaletsa kholo ea moriri.
2.Hair Conditioners
- Li-conditioner le Li-Mask tsa Moriri: E kenyelelitsoe lihlahisoa tsa tlhokomelo ea moriri ho fana ka tšireletso ea antioxidant le ho ntlafatsa bophelo ba moriri.
Lijo le Lino
Lijo tse Sebetsang
- Lino tsa Bophelo bo Botle: Glabridin e ka ekeletsoa ho lino tsa bophelo bo botle le lino tse sebetsang ho fana ka melemo ea antioxidant le e khahlanong le ho ruruha.
- Libaka tsa Phepo: E sebelisoa libakeng tsa phepo le lijo tse bobebe tse reretsoeng ho khothaletsa bophelo bo botle le boiketlo ka kakaretso.
Lipatlisiso le Ntlafatso
Patlisiso ea Biomedical
- Patlisiso ea Kankere: Glabridin e ithutoa bakeng sa thepa ea eona e ka bang khahlanong le mofets'e, ho kenyelletsa le bokhoni ba eona ba ho thibela kholo ea lisele tsa mofets'e le ho etsa hore apoptosis.
- Patlisiso ea Mafu a sa Feleng: E batlisisitsoe ka melemo ea eona e ka bang teng ho laola mafu a sa foleng a kang lefu la tsoekere le mafu a pelo le methapo ka lebaka la thepa ea eona e khahlanong le ho ruruha le antioxidant.
Lipotso Tse Amanang le Ena U ka li Thahasella:
Ho nka nako e kae bakeng sa licorice extractglabridinho khantša letlalo?
Nako eo e nkang hore licorice extract e nang le glabridin e bebofatse letlalo e ka fapana ho latela lintlha tse 'maloa, ho kenyelletsa le bongata ba glabridin sehlahisoang, makhetlo a kopo, mofuta oa letlalo la motho, le ho teba ha hyperpigmentation. Litaelo le maikutlo a akaretsang ke tsena:
1. Nako e Tloaelehileng ea Nako
- Liphetho tsa Pele: Basebelisi ba bang ba ka qala ho bona ntlafatso ea pele ea letlalo le phokotso ea hyperpigmentation nakong ea libeke tse 2 ho isa ho tse 4 tsa tšebeliso e tsitsitseng.
- Liphetho tse Bohlokoa: Litlamorao tse hlokomelehang haholoanyane le tse bohlokoa tsa ho bentša letlalo hangata li etsahala kamora libeke tse 8 ho isa ho tse 12 tsa ts'ebeliso e tloaelehileng.
2. Lintlha Tse Susumetsang Katleho
Mahlohonolo a Glabridin
- Mekhabiso e Phahameng: Lihlahisoa tse nang le likhahla tse phahameng tsa glabridin (mohlala, 0.5% ho isa ho 1%) li ka hlahisa liphello tse potlakileng le tse hlakileng haholoanyane.
- Maemo a tlase: Lihlahisoa tse nang le likhahla tse tlase li ka nka nako e telele ho bonts'a litlamorao tse bonahalang.
Khafetsa ea Kopo
- Tšebeliso ea Letsatsi le Letsatsi: Ho sebelisa sehlahisoa hang kapa habeli ka letsatsi, joalo ka ha ho khothalelitsoe, ho ka ntlafatsa katleho le ho potlakisa liphetho.
- Tšebeliso e sa tsitsang: Tšebeliso e sa tloaelehang e ka liehisa liphello tse bonahalang 'me ea fokotsa katleho ka kakaretso.
Mofuta oa Letlalo le Boemo
- Mofuta oa Letlalo: Batho ba nang le letlalo le khanyang ba ka bona liphetho kapele ha ba bapisoa le ba nang le letlalo le lefifi.
- Bohloko ba Hyperpigmentation: Hyperpigmentation e bonolo e ka arabela ka potlako kalafo, ha linyeoe tse matla haholo li ka nka nako e telele ho bontša ntlafatso.
3. Mokhoa o Tlatsetsang oa Tlhokomelo ea Letlalo
- Tšireletso ea Letsatsi: Ho bohlokoa ho sebelisa setlolo se sireletsang letlalo letsatsing letsatsi le leng le le leng ha u sebelisa lihlahisoa tse khantšang letlalo ho thibela 'mala o mong hape le ho sireletsa letlalo tšenyong ea UV.
- Moisturization: Ho boloka letlalo le le mongobo hantle ho ka ntlafatsa ho monya le ho sebetsa ha lihlahisoa tse nang le glabridin.
- Exfoliation: Ho phunya khafetsa ho ka thusa ho tlosa lisele tse shoeleng tsa letlalo le ho khothalletsa ho kenella ha metsoako e sebetsang, e ka 'nang ea potlakisa liphello.
4. Lithuto tsa Tleliniki le Bopaki
- Lithuto tsa Tleliniki: Liphuputso tse ling tsa kliniki li bontšitse hore glabridin e ka fokotsa haholo hyperpigmentation le ho ntlafatsa letlalo la letlalo nakong ea libeke tse 8 ho isa ho tse 12 tsa tšebeliso e tsitsitseng.
- Bopaki ba Basebelisi: Basebelisi ba bangata ba tlaleha ho bona ntlafatso e hlokomelehang letlalong la bona le phokotso ea matheba a lefifi nakong ea libeke tse 'maloa ho isa likhoeling tse' maloa tsa ts'ebeliso e tloaelehileng.
Ke litla-morao life tsaglabridin?
Glabridin e na le mesebetsi e fapaneng ea likokoana-hloko le melemo ea bophelo bo botle, empa maemong a mang, ho sebelisa lihlahisoa tse nang le glabridin ho ka baka litla-morao tse ling. Lintlha tse latelang ke litla-morao le litemoso tse ka bang teng bakeng sa glabridin:
1. Ho halefa ha Letlalo le Allergic Reactionns
Ho teneha ha Letlalo
- Matšoao: E ka kenyelletsa bofubelu, ho ruruha, ho hlohlona, ho hlaba kapa ho chesa.
- Lisosa: Kutloisiso ea letlalo ho glabridin kapa metsoako e meng ea sehlahisoa e ka baka ho teneha ho honyane ha letlalo.
Mehato ea Allergic
- Matšoao: E ka kenyelletsa lekhopho, erythema, ho ruruha, kapa ho hlohlona ho matla.
- Lisosa: Allergy ho glabridin kapa metsoako e meng ea sehlahisoa, e ka bakang karabelo e fapaneng.
2. Photosensitivity
- Keketseho ea Kutloelo-bohloko ho Khanya ea Letsatsi: glabridin e ka eketsa kutlo ea letlalo ho khanya ea letsatsi, e lebisang ho cheso ea letsatsi kapa photosensitivity dermatitis.
- Thibelo: Ha u sebelisa lihlahisoa tse nang le glabridin, ho kgothaletswa ho sebelisa setlolo se sireletsang letsatsi ka bongata le ho qoba ho pepesehela letsatsi nako e telele.
3. Liphello tsa Hormonal
- Ts'ebetso e ka bang teng ea Hormonal: Le hoja glabridin e reretsoe tšebeliso ea lihlooho, likarolo tse itseng tsa licorice (joaloka glycyrrhizic acid) li tsejoa li na le liphello tse kang steroid tse ka amang ho leka-lekana ha li-hormone.
- Ho nahanela: Ha u sebelisa lihlahisoa tse nang le glabridin ka bongata ka nako e telele, u lokela ho ela hloko ho hlokomela hore na ho na le matšoao a ho se leka-lekane ha li-hormone.
4. Litšebelisano le Lisebelisoa tse ling tsa Skincare
- Litšebelisano tse ka 'nang tsa etsahala: glabridin e ka sebelisana le lisebelisoa tse ling tse sebetsang (tse kang vithamine C, retinol, joalo-joalo), tse amang katleho ea eona kapa ho eketsa kotsi ea litla-morao.
- Keletso: Ha u sebelisa lihlahisoa tse nang le glabridin, ho kgothaletswa ho qoba ho sebelisa lisebelisoa tse ling tse matla tse sebetsang ka nako e le 'ngoe kapa ho buisana le dermatologist pele u sebelisoa.
5. Liphello tsa Tsamaiso
- Monyetla o Lekanyelitsoeng:glabridine sebelisoa haholo-holo bakeng sa tšebeliso ea ka ntle 'me e na le mokhoa o fokolang oa ho monya, kahoo litla-morao tsa tsamaiso ha li tloaelehe haholo.
- Tlhokomelo: Haeba u e-ba le maikutlo a sa thabiseng kapa a sa tloaelehang, u lokela ho khaotsa ho e sebelisa hang-hang 'me u buisane le ngaka ea hau.
6. Bokhachane le ho Anyesoa
- Matšoenyeho a Tšireletseho: Hona joale ho na le lintlha tse fokolang mabapi le polokeho ea glabridin ho basali ba bakhachane le ba anyesang.
- Keletso: Basali ba bakhachane le ba anyesang ba lokela ho buisana le ngaka ea bona pele ba sebelisa lihlahisoa tse nang le glabridin.
Nako ea poso: Sep-21-2024
